With the in-depth implementation of the “Belt and Road” initiative, the demand for compound talents in business English is increasing. However, the existing business English talent training model has not been able to fully meet this demand, and there are problems such as insufficient integration of interdisciplinary knowledge and weak innovation and entrepreneurship capabilities. To this end, this paper introduces the “integration” compound talent training model, which solves the problems of a single goal of business English talent training, lagging behind in training content and methods by optimizing the curriculum system, strengthening practical teaching, and deepening the integration of industry, academia, and research. This study focuses on how to improve students’ comprehensive abilities, especially in cross-cultural communication, international business practice, and minority language skills, through interdisciplinary integration and the introduction of an international vocational skills certification system. Ultimately, by updating talent training goals and innovating teaching methods, students’ professional abilities and employment competitiveness in the field of business English are improved, providing a practical solution to the talent needs under the “Belt and Road” initiative.