Objective: To analyze the application of nursing safety management in orthopedic nursing management. Methods: From January 2015 to December 2015, the Department of Orthopedic Nursing Safety management measures, as well as January 2016 December 2016 during the period of our hospital for orthopedic care safety management measures, the nursing work to sort out the information Statistics, and the two measures before and after the implementation of our hospital orthopedic care level and patient care satisfaction were retrospectively summed up, and the value of the comparison. Results: After the implementation of orthopedic nursing safety management measures, the nursing level of our hospital was obviously improved, and the patient ‘s nursing satisfaction increased significantly, the difference was statistically significant (P<0.05).