A Case of Ventilator-associated Pneumonia in Neonatology: Investigation and Analysis of the Source of Ralstonia mannitolilytica Infection

¹ Department of Infection Control, Peking University First Hospital Ningxia Women and Children’s Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital),Yinchuan 750000, Ningxia Hui Autonomous Region, China,

JCNR 2026 , 10(1), 200–206; https://doi.org/10.26689/jcnr.v10i1.13770

© 2026 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )

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Abstract

This study examined a case of ventilator-associated pneumonia caused by Ralstonia mannitolilytica in a neonatal department in order to determine the source of infection and mode of transmission. Symptoms of infection began to appear on day 16 of admission, and both sputum and catheter tip cultures revealed R. mannitolilytica. The infection control department of the hospital later sampled and identified R. mannitolilytica in the ventilator tube that was used by the patient with the exact gene sequence as the infecting strain. These findings indicate that ventilator tubing is a significant contamination source of this pathogen, and hospitals need to enhance their disinfection methods of ventilator-related devices.

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