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Volume 10,Issue 7

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10 December 2025
Analysis of the Efficacy of High-Flow Nasal Cannula Oxygen Therapy and Non-Invasive Ventilation in COPD Patients
Xue Yin ,  Yan Li ,  Yan Ma ,  Yue Sun ,  Li Li ,  Wenmei Yan ,  Jianhua Zhang ,  He Zhang ,  Haisheng Yang
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1 Department of Respiratory and Critical Care Medicine, Wuhai People’s Hospital, Wuhai 016000, Inner Mongolia Autonomous Region, China,
JCNR 2025 , 9(11), 307–315; https://doi.org/10.26689/jcnr.v9i11.13010
© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
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Abstract

Patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) often suffer from respiratory failure and require respiratory support therapy. High-flow nasal cannula oxygen therapy (HFNC) and non-invasive positive pressure ventilation (NIPPV) are commonly used non-invasive respiratory support methods. HFNC can provide precisely heated and humidified high-flow oxygen, reducing dead space and increasing alveolar ventilation. NIPPV can supply stable high-concentration oxygen and improve gas exchange. This article reviews the application of HFNC and NIPPV in the acute exacerbation stage of COPD, aiming to provide references for reasonable clinical selection.

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