ARTICLE
31 December 2025
Clinical Guideline for Cleansing and Antisepsis in Chronic Wounds
Shouyu Wang Xiaohong Sun Tianke Yang Huan Wang Peng Shi Xingkai Wang
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1 The First Affiliated Hospital of Dalian Medical University, Dalian 116000, Liaoning, China,
2 Department of Nursing, The First Affiliated Hospital of Dalian Medical University, Dalian 116000, Liaoning, China,
3 The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong, China,
4 Affiliated Hospital of Chengde Medical University, Chengde 067000, Hebei, China,
5 Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100000, China,
6 Shanghai Sixth People’s Hospital, Shanghai 200000, China,
JCNR 2025 , 9(12), 16–20; https://doi.org/10.26689/jcnr.v9i12.13411
© 2025 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

This guideline summarizes evidence-based recommendations for cleansing and antisepsis in chronic wounds. It defines target populations, assessment and decision frameworks, preferred cleansing solutions and pressures, indications and limits for antiseptics, biofilm-oriented strategies, pain control, and adaptations for high-risk patients and low-resource settings. The aim is to optimize wound bed preparation, protect viable tissue, reduce infection and iatrogenic injury, and standardize outpatient and home-care practice.

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