Objective: To analyze the treatment effect of standardized bronchoscopic interventional therapy (i.e., interventional therapy) on airway stenosis. Methods: Forty patients with airway stenosis admitted to the hospital between September 2022 and September 2024 were selected and randomly divided into two groups using a random number table. The experimental group received interventional therapy, while the reference group received conventional treatment. The total effective rate, degree of airway stenosis, shortness of breath score, and lung function indicators were compared. Results: The total effective rate in the experimental group was higher than that in the reference group. The proportion of mild stenosis in the degree of airway stenosis was higher in the experimental group than in the reference group. The shortness of breath score was lower in the experimental group than in the reference group. The lung function indicators were better in the experimental group than in the reference group (P < 0.05). Conclusion: Interventional therapy is effective for patients with airway stenosis, as it can reduce the degree of stenosis, improve symptoms of shortness of breath, and protect patients’ lung function.