Based on the retrospect and analysis of the main points of the development of computer management information system, on the basis of the study of relevant data such as enterprise units, mass media, personal information and information security, and according to the actual situation of our country, this paper intentionally and systematically collects relevant research materials on the role of management information system in the survival and development of enterprises, and aims at one or more merits. To study its impact, this paper focuses on three aspects: application analysis, development direction and implementation strategy, which can provide strong reference and guidance for the application of enterprise computer management system.