Research Progress on the Mechanism of Action of Traditional Chinese Medicine Extracts in the Prevention and Treatment of Periodontitis

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Abstract

Periodontitis is an inflammatory infectious disease affecting the periodontal supporting tissues and is the primary cause of tooth loosening and tooth loss in adults. Clinically, supragingival scaling, subgingival scaling, root planing, and other basic periodontal treatments, often combined with antibiotic therapy, are commonly employed with moderate efficacy. However, the increasing prevalence of antibiotic resistance and associated adverse reactions has become a growing concern. Recent studies have demonstrated the significant impact of traditional Chinese medicine (TCM) extracts in both the prevention and treatment of periodontitis, exhibiting remarkable effectiveness. This review explores the role and mechanisms of TCM extracts in the prevention and treatment of periodontitis, providing a reference for further elucidation of their mechanisms and a theoretical basis for the development of Chinese herbal medicine-based care products.

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