Against the backdrop of deepening global economic integration, the position of intellectual property as a core competitiveness is increasingly prominent. However, due to differences in legal systems, economic development levels, and value orientations among countries, intellectual property protection faces serious conflicts and fragmentation issues in international trade. This article aims to explore the coordination mechanism of intellectual property legal norms under the global trade framework, analyze the effectiveness and limitations of current international conventions, and dissect the deep-seated contradictions between developed and developing economies in terms of rights protection and public interest balance. The article proposes that future legal coordination should be based on respecting the diversity of sovereignty, constructing a fairer and more inclusive international rule system, and promoting the stability of the global trade order and the sustainability of innovation-driven development through the benign interaction between multilateral platforms and regional agreements.