In the practical process of college Japanese Teaching, cultivating students' comprehensive language application ability and intercultural communication awareness is an important orientation of teaching activities. To achieve this goal, based on Project-Based Learning (PBL), this paper first analyzes its application value in college Japanese Teaching. Then, combined with practical teaching experience, it puts forward strategies such as anchoring curriculum objectives and designing hierarchical project tasks, focusing on language practice and implementing targeted teaching guidance, basing on the learning process and constructing a diversified evaluation system, integrating internal and external resources and building a practical support platform, so as to provide reference for front-line teachers' teaching.