With the industrial upgrading and the proposal of the Belt and Road Initiative, the cross-border e-commerce industry has developed rapidly. Its dominance in the whole import and export industry has been continuously strengthened, leading to the increasing demand for cross-border e-commerce talents. As the main place for training cross-border e-commerce talents, colleges and universities are far from the needs of the industry in their training of these talents. Therefore, this article analyzes the demand for cross-border e-commerce talents through research, interviews, and data sorting, as well as provides several suggestions for the training of cross-border e-commerce talents in colleges and universities.