Higher vocational education’s international trade major is one of the most significant majors in current vocational education’s popular talent training. Introducing the thinking and mode of cross-border e-commerce, as well as effectively establishing a talent training mode based on career orientation, will not only contribute to the scientific and standardized development of contemporary vocational education, but will also create a new situation in the process of international trade. The effect of talent training is ensured by the new curriculum development method of higher vocational education in the new era ^[1]. This article briefly discusses the training direction and route of international trade professionals from the perspective of cross-border e-commerce, with the goal of making a little contribution to the training of current professional talents.