With the development of the digital economy, virtual reality (VR) technology has gradually become one of the core components of information technology in the new era, widely used in education, medical care and other fields. The market has put forward an urgent demand for VR technical talents with practical and industry adaptability. Vocational and technical colleges shoulder the mission of cultivating skilled talents, and the teaching effect of their VR technology application major affects the talent supply for industry development. However, they also face problems such as disconnection from the industry and insufficient experience of teachers, making it difficult for students to meet the requirements of positions. The application of the school-enterprise integration education model helps break this predicament, promote the connection between education and enterprise practice, give play to the advantages of both parties, and form a new education pattern. From the perspective of the VR technology application major, this paper analyzes the application value of the school-enterprise integration education model and puts forward specific educational practices, aiming to provide reference for colleges and universities to adjust professional education plans.