Based on MOOC, the blended teaching mode of piano in university have shown significant advantages in enhancing teaching efficiency and students’ independent learning ability due to its openness and richness of resources. Traditional piano teaching is mostly a “one-to-one” mode, which is effective, but with high cost and limited coverage, it is difficult to meet diversified learning needs. This study focuses on MOOC-supported blended piano teaching in university, and proposes innovative teaching strategies and practical paths. The study shows that MOOC blended teaching provides a more efficient and flexible solution for piano courses in in university, and puts forward suggestions for optimizing resources and evaluation mechanisms, providing new ideas for innovation in music education in university.