The teaching goal of the higher vocational nursing major is to cultivate nursing talents who can meet the needs of the post. Teachers are required to guide students in learning professional knowledge and basic operation skills, while enhancing students’ service awareness and professional ethics to ensure that they can be competent for clinical nursing work. As teachers, it is necessary to combine the positioning of the higher vocational nursing major and continuously promote the reform of the education mode to keep it in line with the times. Therefore, the author summarizes relevant practical experience, analyzes the key factors affecting the reform of the higher vocational nursing education mode, and puts forward feasible strategies to promote the reform of the higher vocational nursing education mode, to provide a reference for colleagues ^[1].