Under the background of the deep integration of new engineering education development and innovation and entrepreneurship education, there is a widespread structural disconnection between traditional practical teaching and innovation and entrepreneurship education in terms of objectives, content, and form.This study investigates the establishment of a comprehensive “innovation and entrepreneurship + research-learning” practice base for undergraduate electronic information engineering programs, proposing a systematic pathway characterized by “three-stage progression and four-dimensional collaboration.” By constructing a three-stage educational ladder consisting of “cognitive experience, project inquiry, and innovation creation,” and supported by a four-dimensional (safeguard mechanism) encompassing “curriculum system, faculty development, platform management, and evaluation feedback,” the model systematically integrates the college’s existing industry-academy cooperation resources, spatial facilities, and information platforms. Empirical evidence confirms that this model not only provides a systematic framework for supporting multi-tiered activities, including academic competitions, innovation workshops, and science-related volunteer services, but also yields marked achievements in talent development, pedagogical innovation, and research commercialization, thereby offering a replicable and scalable paradigm for achieving deep integration of specialization, innovation, and research in application-oriented undergraduate institutions.