Against the background of rapid iteration of information technology and high-quality development of higher education, university chemistry laboratories, as core bases for chemistry teaching, scientific research innovation and talent cultivation, play a key role in professional talent training quality with their information-based management level and efficiency. Based on this background, this paper briefly analyzes the importance and current situation of chemistry laboratory management in universities under the information age, and discusses optimized countermeasures for university chemistry laboratory management, aiming to provide theoretical references for promoting the high-quality development of university chemistry laboratories in the information era.