This article examines safety management in Chinese university biochemical laboratories, emphasizing the need for improved safety awareness and standardized practices. The study analyzes challenges such as inadequate safety consciousness among researchers, risks associated with chemical reagents, and equipment-related hazards. Comparative insights are drawn from international safety management systems, particularly those in Australian universities. The research proposes solutions including the establishment of a laboratory admission system, strict management of chemical reagents, and the standardization of experimental instrument usage. The findings underscore the importance of rigorous safety protocols and preventive measures to mitigate accidents in university biochemical laboratories.